14th IFAC Symposium on System Identification, SYSID 2006

SYSID-2006 Paper Abstract

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Paper FrA6.6

Falugi, Paola (Univ. di Firenze), Giarre', Laura (Univ. di Palermo)

Parameter Bounded Estimation for Quasispecies Models of Molecular Evolution

Scheduled for presentation during the Regular Session "Identification in Biological Systems" (FrA6), Friday, March 31, 2006, 12:10−12:30, Newcastle Room

14th IFAC Symposium on System Identification, March 29 - 31, 2006, Newcastle, Australia

This information is tentative and subject to change. Compiled on July 16, 2018

Keywords Biological Systems, Bounded Error Identification, Nonlinear System Identification

Abstract

The Quasispecies models identification for Evolutionary Dynamics is considered in a worst-case deterministic setting. These models analyze the DNA and RNA evolution or describe the population dynamics of viruses and bacteria. In this paper we identify the Fitness and the Replication Probability parameters of a genetic sequences, subject to a set of stringent constraints to have physical meaning and to guarantee positiveness. The conditional central estimate and the Uncertainty Intervals are determined. The effectiveness of the proposed procedure has been illustrated by means of simulation experiments while tests on real data are under concern.